CBD for despair: what we all know to this point
What causes depression?
Depression occurs in many different forms and may be the result of a single or multiple factors.
Some of the relevant causes of depression are:
There is no single cause for depression, and for many people, multiple problems can combine to form a depression.
Why Can CBD Oil Help with Depression?
CBD oil is one of the main compounds of the cannabis plant.
In recent years, the popularity has increased, thanks to a significant number of studies, on Many health benefits indicate, including the treatment of depression and other physical ailments.
Many studies indicate the CBD capsules are a potent optionin alleviating the symptoms of depression and possibly treating them.
In a review article published in Surgical Neurology International and examined all the potential benefits of CBD became Depression is one of the conditions where CBD has the potential to be treated.
There are many different reasons why CBD has a potential for treating depression and helping sufferers.
Some of these reasons are listed below.
CBD amplifies the endocannabinoid system
It is responsible for many different aspects of neurotransmission, neuroendocrine and inflammatory processes.
In a paper published in Molecular Medicine Reports each of these processes is harmed in people with depression.
It is known that CBD promotes the function of the endocannabinoid system.
It works on the enzymes within the ECS, which are responsible for the uptake of the endocannabinoids of the body.
With more endocannabinoids present, the ECS can operate at an optimal level.
Since the ECS has significant effects on the processes involved in depressive Patients being harmed, it can be concluded that CBD has potential for the treatment of depression.
A review published in Behavioral Pharmacology investigated the signaling capacity of the endocannabinoid system in patients who were depressed against healthy subjects.
It turned out that depressive subjects showed impaired function of their endocannabinoid system [ThereisalsosignificantevidencetosuggestthatoneofthemajorreceptorsoftheCB1receptorintheendocannabinoidsystemplaysawich
role in depression. In the same review of Behavior Pharmacology the authors studied studies in which the CB1 receptor was blocked in the endocannabinoid system.
They found that patients by blocking this receptor displayed similar symptoms to depression, including decreased appetite, increased anxiety, and stress sensitivity.
The similarities between the symptoms of blockade of the CB1 receptor and the symptoms of depression suggest that improvement of the endocannabinoid system may be a potential form of treatment for depression.
CBD is known to enhance the function of the endocannabinoid system, making it a perfect option for depressives.
Another study looked at how mild genetic defects in the CB1 receptor can affect susceptibility to mood disorders such as depression and anxiety.
It turned out that patients with mild genetic alterations of the CB1 receptor were more susceptible to the development of a mood disorder.
There is clear evidence that dysfunction in one of the primary receptors of the endocannabinoid system leads to depression.
Other depression factors besides the CB1 receptor
While CB1 receptors are an important part of the depression equation, other factors may also play a role.
One of the major causes of depression may be everyday stress .
Acute or chronic stress can often lead to depression and anxiety.
A study in the British Journal of Pharmacology found that CBD can reduce the typical responses to stress in rats.
Scientists who conducted the study made various stressful experiences in rats, including an elevated labyrinth test, an animal model to test stress, and periods of restraint.
Researchers studied the reactions of rats to these stressful events. One group of rats received CBD while another received a placebo.
The researchers found that the stress responses of rats receiving CBD were significantly lower than those of rats who did not.
This led to the conclusion that CBD has the potential to reduce general stress reactions.
In another study, "Beyond the CB1 receptor: is cannabidiol the answer to motivational disorders?" looks at how CBDs look like Effects on stress can lead to less anxiety and depression.
They came to the conclusion that the potential of CBD to reduce stress could lead to a reduction in depression symptoms.
CBD Oil Helps the Brain to Grow
Another promising option for CBD to help people with depression is the mechanism by which hippocampal neurogenesis is promoted becomes.
Hippocampal neurogenesis is the growth of new neurons in the hippocampus of the brain.
A study published in Neuropsychopharmacology investigated the ways in Increasing neurogenesis of the hippocampus in adults could alter the effects of both anxiety and depression.
They found that by the increase of hippocampal neurogenesis the symptoms of anxiety and depression have been reduced.
In a study in which two groups of mice were exposed to constant and repeated stress factors, the group of mice receiving CBD showed marked decreases in anxiolytic symptoms as well as hippocampal neurogenesis in both depressive and depressed patients.
A review of all the studies on hippocampal neurogenesis and on cannabinoids concluded that the endocannabinoid system and its receptors play an important role in the Trigger neurogenesis play.
The review published in the British Journal of Pharmacology looked at the various stages of neurogenesis and attempted to gain a better understanding of how the body's own Endocannabinoids and plant cannabinoids might play a role in neurogenesis.
While the review did not identify the exact mechanisms by which CBD and endocannabinoids affect hippocampal neurogenesis, it concluded that they are compromised. Neurogenesis is both a trigger for depression and a major depressive disorder Impairment of brain function.
This led the authors of the study to conclude that CBD and the alteration of the endocannabinoid system have tremendous potential in treating and supporting this had mood disorders like depression.
Reduction of Inflammation
Although it is still uncertain whether inflammation is an actual cause of depression, there are studies that suggest that inflammation is possible Be an important predictor of whether other treatments for depression are working or not.
One study examined the influence of inflammation on treatment-resistant depression.
It turned out that 45% of patients with refractory depression also suffered from inflammation.
Another study discovered that inflammatory markers could be used as a reliable predictor of the efficacy of standard antidepressants.
In a study titled
researchers were able to investigate how severely a patient was inflamed and accurately predict whether an antidepressant would act as a treatment " Cannabinoids as novel anti-inflammatory drugs " Researchers analyzed how CBD and other cannabinoids can reduce or affect inflammation throughout the body.
They came to the conclusion that CBD can act as an anti-inflammatory substance throughout the body.
It is necessary to investigate the ways in which the inflammation targeted by the CBD affects depression.
However, since inflammation is a key indicator of the effectiveness of antidepressants, there is reason to believe that CBD has the potential to aid the treatment of depression by reducing its inflammation.
CBD oil against anxiety and depression: what's wrong?
In the worst case, depression can lead to suicidal thoughts and sometimes to suicide
Because antidepressants have not completely resolved the problem of depression, they find new and new ways to treat this disease are a matter of life and death.
According to the American Foundation for Suicide Prevention, over 50 percent of people who die from suicide suffer from major depression.
This statistic springs to the forefront when it comes to including depressed alcoholics over 75 percent.
Suicide is the tenth most common cause of death in These tragic numbers illustrate the severity of the problem and the urgent need for a solution ng n.
In a study entitled "High on Life? Medical Marijuana Law and Suicide " investigated the correlation between states that had legalized cannabis and suicide rates.
They found that in states where cannabis was legalized, suicide rates for men between the ages of 20 and 29 are 11 percent and suicide rates for men between 30 and 39 are 9 Percent fell and the total suicide rate fell by 5 percent.
When states legalize cannabis, alcohol consumption tends to decrease along with depression rates.
The authors of the study believe that legalizing cannabis can reduce suicide, as cannabis affects depression and reduces alcohol consumption in men.
This is just a study and more research is needed on this topic.
However, it shows an exciting promise of the psychic benefits that CBD and the cannabis plant provide for the depressive.
Worldwide, more than 300 million people are affected by depression each year.
With these alarming statistics, many companies and scientists are searching for new and novel ways to cure this debilitating and mysterious state of mind.
CBD oil for depression is one of the newest and most popular options for those who are looking for an alternative to pharmaceutical intervention.
CBD helps people with depression in various ways. CBD promotes the function of the endocannabinoid system, which is an integral part of physical and mental health.
CBD is promising in the induction of hippocampal neurogenesis, a type of brain cell growth that, according to some studies, may lead to a reduction in the symptoms of depression.
CBD also reduces inflammation.
While inflammation may or may not be a direct cause of depression, recent data suggests that inflammation can reduce the effectiveness of some of the most common treatment options.
CBD is not a definitive answer to depression because research into this exciting compound and its effects on depression is still in its early stages.
If more research is done, CBD may be one of the best options for people with depression.
Hopefully, this natural botanical compound can help scientists and physicians decode this global scourge of mental health.