The paper goes on to say that hypnotics are often prescribed without an approved indication, usually with specific contraindications, but even if stated, they have little or no benefit.
It is also believed that the recommended doses hardly or not at all increase sleep, and that performance often gets worse and no better during the day.
Kripke also argues that the lack of general health benefits in advertising is often misrepresented.
What about over-the-counter sleeping pills?
They might be safer than prescription hypnotics, but they still have their own drawbacks.
One of the main ingredients in OTC sleep medicine is antihistamine diphenhydramine – sure, it helps you fall asleep, but it's not a promise the sleep you'll get will be peaceful
"The use of diphenhydramine is associated with the onset of Alzheimer's disease, although the cause and effect are unclear," Kripke told Project CBD.
The well-known aspect of diphenhydramine is that it is anticholinergic [blocks the neurotransmitter acetylcholine] that sometimes causes some cardiac symptoms and digestive symptoms such as constipation, and in some patients, diphenhydramine also causes quite a lot of vi at night drowsiness on the day.
OTC sleep aids may also be toxic to the liver as they contain acetaminophen.
Do not read the warning Labels on these readily available sleeping pills, in combination with other medicines and / or alcohol, can be problematic or even fatal.
These tablets should not be taken for more than two weeks.
However, many people use them for much longer than a few weeks.
Do you still want to grab Tylenol PM or this prescription sleeping pill?
Why not think about it? Trying if cannabis can help?
Cannabis for sleeping: Is CBD or THC better?
When it matters, is CBD or THC better for sleep?
Before we go into this question, let's take a look at how the endocannabinoid system plays an important role in sleep.
Sleep and the Endocannabinoid System Are you aware that the way we fall asleep, fall asleep and wake up is closely linked to the endocannabinoid system and our own circadian rhythms?
There is, in fact, a close relationship between the two, which manifests itself in sleep. Wax cycle changes in anandamide and 2-AG, the endogenous cannabinoid compounds of the brain.
Also in the context of sleep-wake cycles, there is a strong relationship to the enzymes that break down these compounds.
At night the content of anandamide in the brain is higher. This compound interacts with neurotransmitters in the brain to make a person sleep.
On the other hand, 2-AG levels are higher throughout the day, suggesting that researchers consider this compound to be more alert.
Both anandamide and 2-AG have been shown to activate CB1 receptors in the central nervous system, including brain regions associated with sleep regulation.
It is believed that they activate CB1 receptors A critical component in mitigating sleep homeostasis.
Both CBD and THC have a strong effect on the endocannabinoid system.
The research in which cannabinoid is "better" is a mixed bag.
Both clinical and anecdotal evidence shows that both can be calming or alarming, depending on how much is taken.
Let's take a closer look.
CBD vs. THC for Sleep
THC and S leep
A 1976 study found that the effects of THC administration on sleep are very similar to those of lithium.
It is no secret that THC contains sedative properties.
It's just the nightcap needed to get the sleep they need.
CBD and Sleep
Unlike THC, CBD is not exhilarating cating.
It has actually been shown that non-psychoactive cannabinoid increases alertness. Instead of acting as a sedative, it is shown that CBD acts as a wax-promoting substance.
How exactly can CBD help you sleep better?
It depends How the cannabinoid interacts with the body's endocannabinoid system.
We have just explained how the endocannabinoid system is closely related to our sleep patterns.
And as we have learned in the past, CBD is excellently suited for the homeostasis of the endocannabinoid system.
Cannabinoid is not only responsible for promoting alertness, but has also been proven to help people fall asleep and fall asleep … and stay awake the next day.
Some researchers claim that CBD may actually be an effective remedy for people with narcolepsy or may be suffering from excessive daytime fatigue.
People who use CBD to sleep swear by taking the desired portion 1-2 hours before bed and giving the cannabinoid time to work its magic.
When it comes to getting the right dose of CBD (and THC) to sleep better, everyone is different.
Cannabis is very human as medicine and what works for one person does not always work for the next.
Both CBD and THC can help you sleep.
What is better?
Ultimately, it's up to you to decide … but our research makes us believe that the general CBD could be better.
This is especially true for the majority of the population as well as for those who do not like to be psychoactive effects that contains THC.
Note that the choice between THC and CBD does not have to be mutually exclusive!
Yes, it is true that you can really have the best of both worlds.
There are tons of products on the market (allowing legal access to THC for medical or recreational use), which are balanced mixtures of THC and CBD.
It is known that CBD mitigates the negative side effects people often experience with THC (anxiety, paranoia or "getting too high").