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What’s CBG? (All About Cannabigerol)

Why?

THC and CBD (and some other cannabinoids) start as CBG!

Basically, without CBG we would have no other.

CBG can be considered a "mother cannabinoid" for THC. CBD and other cannabinoids.

Basically, it is a building block on which several other cannabinoids depend and which plays a very important role in the cannabis plant.

Let's take a closer look.

What is CBG?

As mentioned earlier, CBG is the "mother" cannabinoid of many other cannabinoids found in the cannabis plant.

Essentially, it is classified as a minor cannabinoid, but CBG is an extremely important cannabis compound.

CBG is present in the cannabis plant in the form of cannabigerolic acid (CBGA), the building block of the three main branches of cannabinoids, which include cannabidiolic acid (CBDA). Tetrahydrocannabinolic acid (THCA) and cannabichromenic acid (CBCA).

CBGA converts into these three branches of cannabinoid through specific enzymes known as synthases when the cannabis plant matures.

Because most CBGA is synthesized in these other molecular structures, very low concentrations of this cannabinoid are found in mature cannabis plants.

By a In the process known as decarboxylation (in which the acidic forms of these cannabinoids are heated), CBGA, CBDA, THCA and CBCA each lose one carbon group.

They are then converted to the more popular forms of CBG, CBD, THC and CBC.

This is considered the active state of these compounds, which contains most of the therapeutic benefits.

What Are the Benefits of CBG?

Like other cannabinoids, CBG has shown numerous therapeutic benefits and could play an integral role in various health disorders and diseases.

CBG is not psychoactive, which means it doesn't get you up.

Similar to CBD, it is believed that CBG can combat some of the negative effects of THC-rich strains such as paranoia and anxiety.

CBG has been shown to be a partial agonist of CB1 receptors (those found in high concentrations in the central nervous system), which explains why it may weaken the effects of THC.

While CBG has some binding affinity for CB2 receptors, the mechanisms here are not as well known.

In a review from 2010 neuroscientist and endocannabinoid expert Ethan Russo highlighted some of the promising benefits that research on CBG has discovered ,

Some of the most important discoveries found in this article are:

  • Muscle relaxant: CBG has a stronger GABA uptake inhibition as both CBD and THC, which "could indicate muscle relaxant properties".
  • Pain Relief: According to Russo, the analgesic (analgesic) properties of CBG exceed those of THC.
  • Anti-cancer: It is believed that CBG is the second most effective phytocannabinoid against breast cancer after CBD. It is also believed to be an effective agonist for "potential use in prostate cancer".
  • Antidepressant: More than one study suggests that CBG contains antidepressant properties.
  • Antifungal: Studies show that CBG is an effective remedy for MRSA on its ability to inhibit keratinocyte proliferation.

    He also suggested that CBG could help with overactive bladder and bladder pain.

    A 2015 study supported this suggestion by examining the effects of CBG and other cannabinoids on bladder dysfunction.

    The results showed that CBG and THCV had the greatest ability to reduce bladder contractions.

    Another thing Russo expressed was that CBG could work in synergy with other cannabis compounds, namely terpenes like limonene, linalool, phytol and caryophyllene. Entourage effect .

    A 2016 study examined the neuroprotective properties of CBG in patients with Huntington's disease, a disease that progressively degrades Causes nerve cells in the brain.

    Symptoms of Huntington's include involuntary movements, muscle problems, and more.

    The study found that CBG is "extremely active as a neuroprotective agent" and contributes to the improvement of motor deficits in animal models.

    The study concluded that the discoveries they made opened "new research paths" for the use of CBG and other cannabinoids in neurodegenerative diseases such as Huntington's.

    A study from 2007 found that CBG (and other cannabinoids) can stimulate bone marrow growth indirectly via the CB2 receptor ,

    Does CBG have the potential to heal broken bones? It is possible, although further research is certainly required.

    A 1990 study examined the effects of CBG and THC on glaucoma and found that both cannabinoids increased 2-3 fold watery discharge activity, suggesting that cannabigerol and related cannabinoids may have therapeutic potential in the treatment of glaucoma.

    ]

    Is CBG Rare?

    Here's the thing.

    Although CBG is one of the most important cannabinoids, there are… it is not as readily available as other cannabinoids.

    This is because CBG typically exists as cannabis plants are converted to other cannabinoids as the cannabis plant matures.

    However, this could change as both extraction technology and cannabinoid research are advancing.

    What is the future of CBG?

    Is there a future for CBG?

    Preliminary research into cannabinoids indicates considerable potential.

    CBG may have a future, but there are currently not many opportunities to buy pure CBG oil.

    One day this could change.

    There are currently many professional breeders producing and researching new varieties of CBG-dominant cannabis plants.

    ] shows that the CBG level in the cannabis plant is highest at week 6 of 8 during flowering.

    This offers the possibility of CBG extraction in the early stages of the flowering cycle, which we may see more of in the future.

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